A practical introduction to viral phylogenetics

Exercises

Section 5: big trees

Have a look at Cov2Tree, a website that displays all 6M public SARS-CoV-2 sequences in a phylogenetic tree.

Firstly again have an explore of the tree. Try finding all sequences from England, or the PANGO lineage that emerged in Kent, Alpha, which is called B.1.1.7 in Pango terms.


Find the sequence with GenBank accession (not name) OX303729.1.

Question: What country is this sequence from?
Question: In what country do you think this person acquired the virus?
Question: Based on the data on the tree, is it potentially possible that this person passed on this virus to someone else who was also sequenced?
Question: Based on the tree, where is the most likely place that this clade was imported into the country from?
Question: Is this the only possible country, or could it have come from somewhere else?